Pioneering Psychedelic Research in Pakistan —
Driving Novel Drug Discovery through Genomics and Bioengineering
Pioneering Psychedelic Research in Pakistan —
Driving Novel Drug Discovery through Genomics and Bioengineering
About Us
We are Asia’s pioneering psychedelic biotech company, officially incorporated with the Securities and Exchange Commission of Pakistan and registered with the Federal Board of Revenue since 2021.
We develop research-based, natural treatments for mental health using psilocybin mushrooms—bridging ancient wisdom with modern science by providing standardized, research-grade entheogenic material accessible for global scientific inquiry — filling critical gaps in psychedelic research infrastructure.
We aim to unlock new treatments for depression, PTSD, neurodegenerative disorders, and spiritual disconnection.
With our cultivation facility in Islamabad and a decade-long genetic bank, we are leading a movement that blends nature, innovation, and healing.
Our Mission
Through in-vitro biosynthetic replication, genomic analysis, and molecular-level process development, we explore and enhance the therapeutic potential of natural compounds like psilocybin and other alkaloids. We are committed to developing protocols and biotechnologies that enable precision psychedelic research, drug discovery, and future clinical integration.
Our work is particularly vital in the field of mental health, where there is an urgent need for more effective, biologically targeted, and scalable treatment options.
Mystical Fungi and Flora is changing the landscape of mental and spiritual health by providing innovative and novel solutions rooted in both science and nature.
Our Story
Origins in Ethnobotanical Science
After more than a decade of research and experiential work with naturally occurring entheogens—including flowering plants such as Ipomoea tricolor (morning glory), Argyreia nervosa (Hawaiian baby woodrose), Anadenanthera peregrina, and a diverse range of psychedelic fungi—we formally incorporated Mystical Fungi and Flora Pvt. Ltd. in 2021. Our early work was driven by a scientific and ethnobotanical inquiry into the molecular and biochemical mechanisms underlying consciousness-altering effects, with a focus on identifying, characterizing, and preserving bioactive alkaloids and secondary metabolites. This foundation has informed our mission to translate traditional plant and fungal knowledge into rigorous, research-grade biotechnology applications.
Collaboration with Regulatory and Scientific Bodies
In our journey, we have engaged with key governmental and regulatory bodies to ensure our work remains transparent, compliant, and future-ready. We have maintained close communication with the Ministry of Narcotics Control of Pakistan to discuss strategic frameworks for the investigational development of entheogen-based therapeutics. For regulatory alignment, we have held meetings and consultations with the Drug Regulatory Authority of Pakistan, while collaborating with other oversight bodies to ensure the highest standards in our research processes. For scientific exploration, we maintain active contact with the Pakistan Council of Scientific and Industrial Research, fostering psychedelic research partnerships that advance genomic studies and bioactive compound discovery.
Legal Recognition and Global Research Network
Our commitment to legality and ethics was strengthened by a landmark judgment from the Honorable Islamabad High Court, which recognized the medicinal and research use of psilocybin mushrooms in Pakistan. Over the years, we have worked alongside both national and international institutions for advanced genomic research, building a network of expertise that supports our mission. Today, Mystical Fungi and Flora stands as a pioneering force in Asia’s psychedelic biotechnology space—uniting nature, science, and innovation to unlock the therapeutic potential of the entheogenic world.
What We Do
Standardized, Strain-Specific Cultivation
Standardized, Strain-Specific Cultivation
Standardized, Strain-Specific Cultivation
We cultivate genetically verified strains of Psilocybin mushrooms and related species under tightly controlled environmental conditions to ensure consistent alkaloid expression and therapeutic reliability across every batch.
Genome Sequencing & Molecular Analysis
Standardized, Strain-Specific Cultivation
Standardized, Strain-Specific Cultivation
We conduct whole-genome sequencing and advanced molecular analysis of psychedelic and medicinal fungi and plants to decode their biosynthetic pathways, assess genetic variability, and map unique alkaloid profiles. This foundational research enables precision cultivation, novel discovery, and strain optimization.
Genetic Engineering & Strain Enhancement
Standardized, Strain-Specific Cultivation
Genetic Engineering & Strain Enhancement
Our work focuses on boosting therapeutic compound production, enhancing cultivation efficiency and yield, and designing customized psychedelic strains with specific alkaloid profiles for clinical applications.
Enzyme Discovery & Drug Development
Spiritual & Clinical Application Studies
Genetic Engineering & Strain Enhancement
Our psychedelic research pipeline actively identifies novel enzymes and bioactive molecules from fungi and plants that may serve as lead compounds for new psychiatric and neurological drugs, act as synergistic co-therapies in psychedelic-assisted treatment, and target mental health, neurodegeneration, and autoimmune disorders. These discoveries lay the foundation for future clinical trials.
Spiritual & Clinical Application Studies
Spiritual & Clinical Application Studies
Spiritual & Clinical Application Studies
Bridging traditional wisdom with modern science, we conduct interdisciplinary research into the spiritual, psychological, and neurological impact of psilocybin. Our goal is to inform integrative therapeutic protocols rooted in both cultural heritage and empirical evidence.
Research & Development
Genome Discovery
Our Development Pipeline
Our Development Pipeline
Whole‑genome sequencing of our proprietary Psilocybe strain has mapped 3,667 proteins and uncovered multiple novel biosynthetic gene clusters (BGCs). These genetic blueprints produce not only psilocybin and related tryptamines but also terpenes, polyketides, phenolic compounds, and no ribosomal peptides — a diverse molecular library with wide‑ranging therapeutic potential.
Our Development Pipeline
Our Development Pipeline
Our Development Pipeline
Our discoveries follow a structured research pathway:
Genome Mapping & Bioinformatics – Identifying and characterizing biosynthetic pathways.
Analytical Validation – LC‑MS, HPLC, and molecular structure confirmation.
ADME & Safety Profiling – Predicting absorption, distribution, metabolism, excretion, and toxicity.
Preclinical Evaluatio
Our discoveries follow a structured research pathway:
Genome Mapping & Bioinformatics – Identifying and characterizing biosynthetic pathways.
Analytical Validation – LC‑MS, HPLC, and molecular structure confirmation.
ADME & Safety Profiling – Predicting absorption, distribution, metabolism, excretion, and toxicity.
Preclinical Evaluation – Testing for neuroactivity, anti‑inflammatory, and antimicrobial effects.
This approach ensures each candidate moves efficiently from nature’s genetic code to investigational drug status.
Therapeutic Potential
Our Development Pipeline
Therapeutic Potential
Our genome‑driven platform expands Psilocybe research beyond psilocybin to address mental health, neurodegeneration, immune modulation, and infectious disease. Several biosynthetic pathways are uncharacterized in any known organism, representing rare opportunities for first‑in‑class medicines. This positions us to lead the next wave of psychedelic and natural product drug innovation.
Contact Us
At Mystical Fungi and Flora, we welcome collaborations, scientific inquiries, and discussions with researchers, clinicians, and institutions exploring the therapeutic potential of psychedelic compounds. Whether you’re seeking research-grade material, partnership opportunities, or specialized consultation, our team is here to connect.
